The results from RT-qPCR assays in PTEN-null GBM cells, such as U87, PTEN-KO SF763, and U251 cells, revealed that PATZ1 and PRRX1 were upregulated upon shRNA-mediated LOX depletion and the treatment with LOX inhibitor BAPN (Figure 5, E and F and Supplemental Figure 5, C and D). This evidence concerns the gene PRRX1 and glioblastoma.