PTEN and glioblastoma: To further validate the function of NF-κB-PATZ1 signaling axis in regulating OLFML3 in GBM cells, we overexpressed PATZ1 in PTEN-KO SF763 cells (Supplemental Figure 5H) and found that PATZ1 overexpression enhanced OLFML3 expression and abolished P65 activation–induced downregulation of OLFML3 (Figure 5K).