Similarly, pharmacologic inhibition of LOX using the inhibitor BAPN increased the expression of OLFML3 in both human (e.g., U87, PTEN-KO SF763, GSC23, and GSC7-10) and mouse (e.g., CT2A and 005 GSCs) GBM cells and GSCs (Figure 3, D and E and Supplemental Figure 3C). This evidence concerns the gene LOX and glioblastoma.