In patients with delirium, we observed strong correlations between the SBT at three months and Tau protein at day 3 (r = 0.675, p = 0.016), E-Selectin at day 7 (r=-0.617, p = 0.043) and UCHL-1 at discharge (r = 0.936, p < 0.001) (Additional file 2). This evidence concerns the gene MAPT and delirium.