Some circulating factors, i.e. vascular endothelial growth factor (VEGF), have also been linked to cancer-associated MCD: in a case report of MCD associated with colon cancer [48], the development of glomerular disease was linked to VEGF levels, and tumor excision provoked a decrease in VEGF levels and prompt remission of the nephrotic syndrome. The gene discussed is VEGFA; the disease is colonic neoplasm.