TNF and incontinentia pigmenti: Our data suggest that the thymic hypotrophy and dysplasia observed in IP result from TNF-mediated cell death (Senegas et al., 2015; Pescatore et al., 2016; Pasparakis et al., 2002; Nenci et al., 2006), probably of TECs (Makris et al., 2000; Rudolph et al., 2000; Schmidt-Supprian et al., 2000).