AKT1 and glioblastoma: It has been described so far that the inhibition of transmission by PI3K-AKT/PKB-mTOR increases the sensitivity of glioblastoma cells to the induction of programmed death, and combination therapy, especially with natural compounds, enhances the anticancer potential of clinically used treatment (Jakubowicz-Gil 2009; Schwartzbaum et al. 2006).