NLRP11 (also known as NALP11, NOD17, PAN10, and PYPAF6) is an enigmatic NLR protein with its expression found in maturing oocytes from humans and rhesus macaque monkeys, and to a lesser extent in the monocytic cell line THP‐1, B cell lymphoma cell line Daudi, and primary CD19+ B cells derived from humans.65, 110, 111, 112, 113. This evidence concerns the gene NLRP11 and B-cell non-Hodgkin lymphoma.