Apabetalone (BET protein inhibitor) reduced HF hospitalisation and cardiovascular death.201miR210 targeting glycerol-3-phosphate dehydrogenase gene and protected against ischemic injury.195CDR132L (miR132 inhibitor) reduced plasma miR-132 and NT-proBNP levels in chronic HF.202Givinostat/ITF2357 (HDAC inhibitor) prevented left ventricular diastolic dysfunction.196. Here, NPPB is linked to Left ventricular diastolic dysfunction.