In women with PCOS, there is a positive correlation between the AMH concentration and the LH/FSH ratio as well as the level of LH, testosterone, dehydroepiandrosterone sulfate (DHEA-S), total cholesterol, low-density lipoprotein (LDL) and the FAI (free androgens index), which is the quotient of free testosterone and sex hormone binding globulin (SHBG), fasting insulin level and HOMA-IR (homeostasis model of assessment-insulin resistance) (133, 137, 138). The gene discussed is SHBG; the disease is polycystic ovary syndrome.