Therefore, Western blot analysis from hippocampal homogenates for total TrkB, the TrkB.T1 isoform ratio, ERK, AKT, and PLCγ, along with a suite of behavioral measurements, were conducted following two weeks of daily rTMS in both 3xTg-AD and B6 wild-type mice. The gene discussed is MAPK1; the disease is Alzheimer disease.