Several genes included in the predictive lipid-related gene signature have not yet been studied in the context of breast cancer, which include ACAA2, ACSF2, AGPAT3, AGPAT6, APOA5, ARSK, BDH2, CBR4, ACOT13, ACOT11, MVK, OLAH, ACADSB, ACOX1, IVD, LCLAT1, MGLL, SLC44A4, PLAAT1, PLAAT5, and PITPNM2. The gene discussed is CBR4; the disease is breast cancer.