In humans, where CRP is an acute phase protein produced during inflammatory states (62), this property of CRP can protect the host against inflammatory diseases involving malfunctioning proteins such as atherosclerosis in which LDL is ectopically deposited in the arteries, in pneumococcal infection where complement inhibitor factor H is deposited on pneumococci and in inflammatory arthritis in which immune complexes are formed, assuming that these proteins expose Aβ-like structures after deposition at places where they are not supposed to be (63–65). This evidence concerns the gene CRP and pneumococcal infection.