Concluding, 5-month-old NSPHs are immune responsive to pro-inflammatory stimulation and SeVeGFP-infection, as demonstrated by the secretion of IL-6 and CXCL10, but do not secrete pro-inflammatory cytokines following VZVeGFP-ORF23-infection, at least not for the panel applied in this study. This evidence concerns the gene IL6 and infection.