Conway et al. (2020) simulated the process of kidney damage and repair by establishing mouse UUO and RUUO models and conducted a scRNA-seq analysis of the renal cortex at different time points. Their study revealed heterogeneity of myeloid cells during this process. Arg1+ pro-inflammatory monocytes are recruited during the early stages of injury. Ccr2+ macrophages accumulate in the late stage of injury, while Mmp12+ macrophages may be related to the repair of kidney injury. In this study, we downloaded the sequencing dataset by Conway et al. (2020) (GSE140023) and performed a reanalysis. Here, MMP12 is linked to Nephropathy.