APC and heart disorder: The activated CD4+ T-cell-derived exosomal miR-142-3p regulates the adenomatous polyposis coli (APC)/glycogen synthase kinase-β (GSK-β)-β-catenin signaling cascade to activate WNT signaling pathway and fibroblasts, play a pro-fibrotic role, and lead to rational ventricular remodeling in heart disease.