Danhong Injection-induced endothelial exosomes (DHI-exo) into the myocardial infarction area of MI Mouse can inhibit the apoptosis proteins (p53, Bak, Bax) of cardiomyocytes, thereby protecting the damaged myocardium, which is mediated by increasing the expression levels of miR-125b and regulating p53 signaling pathway (179). This evidence concerns the gene TP53 and myocardial infarction.