ANGPTL2 and type 2 diabetes mellitus: Similarly, patients with diabetic foot ulcer (DFU) exhibited elevated ANGPTL2 levels when compared to subjects with T2DM only (T2DM vs. DFU: 4.221 ± 1.301 vs. 6.561 ± 2.335 μg/L, p < 0.0001) [15].