ANGPTL2 and type 2 diabetes mellitus: The mean of ANGPTL2 was 4.46 ng/mL in the CSME, 3.80 ng/mL in the nCSME group, and 3.33 ng/mL in the control [13], which is similar to our results, where we found that serum ANGPTL2 levels are significantly higher in cases of NPDR and PDR as compared to T2DM without DR.