IL2RA and type 1 diabetes mellitus: Studies have indicated that the interleukin two receptor subunit alpha (IL2RA) gene is closely related to the onset of T1D (Pahkuri et al., 2023), and IL2RA is also implicated in the pathogenesis of SLE and RA (Gorji et al., 2019; van Steenbergen et al., 2015).