Interestingly, we observed a positive correlation between BAP1 expression and the level of tumor-infiltrating immune cells, including CD8+ T cells, NK cells, CD4+ T cells, macrophage, neutrophil and dendritic cells, but not Myeloid-derived suppressor cells (Fig. 1D, Supplementary Fig. S1A) in pancreatic cancer tissues [19]. Here, CD4 is linked to familial pancreatic carcinoma.