Moreover, we generated control and Bap1 knockout KPC (KrasG12D/+; LSLTrp53R172H/+; Pdx-1-Cre) mouse pancreatic cancer cell lines (Fig. 1E) and established the mouse syngeneic subcutaneous pancreatic cancer model (Supplementary Fig. S1B-C). This evidence concerns the gene BAP1 and pancreatic neoplasm.