In order to explore the underlying factors contributing to mitochondrial fragmentation and remodeling of MRC in HGG, we then performed bioinformatics analysis on RNA-seq data obtained from LGG, GBM (which was the highest type of HGG), and normal brain tissues using TCGA and GTEx databases (Specific information was provided in Supplementary Table 1). Here, CD200 is linked to glioblastoma.