To investigate the consistency of ORC6 silencing across various primary NSCLC cells, the lentivirus expressing shORC6-2# was introduced into primary human NSCLC cells derived from different patients, namely, pNSCLC-2, pNSCLC-3, as well as into the A549 immortalized cells (see Fig. 2). Here, ORC6 is linked to non-small cell lung carcinoma.