CD4 and neoplasm: A higher proportion of tumor-infiltrating CD8+ T cells in the thimerosal treatment group expressed the T cell activation marker CD69, CD25, and effector molecules GZMB and IFN-γ, as compared with the control group; Meanwhile, thimerosal treatment decreased the infiltrated frequency of macrophages but not that of CD4+ T cells, NK cells or B cells (Fig. 6F–J; Appendix Fig. S8E–L).