CDH1 and gastric cancer: As shown in Table 1, CDH1 mutations were significantly associated with non-gastroesophageal junction (GEJ) cancer (12.4% vs. 1.5%), younger age (median 57 vs. 64 years old), female (12.7% vs. 8.0%) and diffuse histology (26.8% vs. 1.4%) GC (p < 0.05).