SOX4 and lung carcinoma: Previous studies have confirmed that SOX4 is highly expressed in NSCLC samples and is associated with poor prognosis in patients [37]; Sun J et al. reported that the SOX4/β-catenin axis promotes the self-renewal of lung tumor cells, thereby driving the progression of lung cancer [38]; Chang J et al. confirmed that miR-363-3p inhibits NSCLC invasion and EMT by regulating SOX4 [39].