Whereas, the distribution of CD68 and CD163 positive staining cells, markers for M2-type macrophages, showed no significant difference between groups with low and high Gαi3 expression, hinting a limited effect of Gαi3 on the infiltration of M2 macrophages in the pancreatic cancer TME (Fig. 11F). The gene discussed is CD163; the disease is pancreatic neoplasm.