MTOR and neoplasm: As described in this manuscript and the tables, research involving the treatment of mTOR inhibitors alone or in combination with other anticancer drugs on various types of CSCs has demonstrated that inhibiting the mTOR pathway suppresses not only CSC differentiation into tumor cells but also intrinsic stem cell properties, such as self-renewal and uncontrolled proliferation [161–163, 178, 182, 197, 198].