BCL11B and neoplasm: Identified as a core member in the SWI/SNF complex and a haploinsufficient (intolerant to the loss of a single allele) tumor suppressor, Bcl11b attenuation in Apcmin/+ mice promotes intestinal tumorigenesis, which may be attributed to the increased expression of Wnt/β-catenin targets in Bcl11b-enriched Lgr5+ CBCs.