INS and type 2 diabetes mellitus: On the other hand, Dunstan et al. found that short-term circuit training (3 days/week for 8 weeks) in metabolically well-controlled type 2 diabetes subjects, did not improve insulin area under the curve after oral glucose load [38], thus suggesting the presence of other mechanisms behind the modification of beta cell secretory capacity after exercise or, at least, a more effective secretion of insulin (same amount of released insulin, better peripheral effect on insulin-dependent tissues).