Moreover, genes already associated with cardiomyopathies (BAG3, DSP, PKP2, RYR2, SCN5A, or TNNI3) have been reported as mimicking acute myocarditis.43–45 Surprisingly in our series, we found a large number of patients carrying variants predicted to cause electrical or structural cardiac anomalies. This evidence concerns the gene RYR2 and acute myocarditis.