In this study, we aimed to generate human induced pluripotent stem cell (hiPSC) lines from a PXE patient carrying heterozygous mutation c.3421C > T, p.Arg1141X in the ABCC6 gene to establish an efficient in vitro disease model that can be used for studying disease mechanism specifically in patient-derived cells. This evidence concerns the gene ABCC6 and pseudoxanthoma elasticum (inherited or acquired).