These parameters encompass age, preoperative serum PSA levels, magnetic resonance imaging (MRI), tumor size, GS, Grade Group (GG), and other prognostic factors like lymphatic, venous, perineural, and seminal vesicle invasion, as well as extraprostatic extension (EPE), positive surgical margins (PSM), and lymph node metastasis [12]. This evidence concerns the gene KLK3 and neoplasm.