In READ patients, BMX was significantly downregulated in young adults (21-40 years), middle-aged adults (41-60 years), and elderly (81-100 years) patients compared to the normal population (all p < 0.05), while there was no significant difference in its expression between older adults (61-80 years) and the normal group (p > 0.05). The gene discussed is BMX; the disease is reading.