Interestingly, in the reviewed cases of Pseudo-Meigs' syndrome caused by gastric cancer, including our case, CA-125 levels were elevated to < 500 U/ml, even in the presence of massive ascites, suggesting that CA-125 may not be a reliable marker for distinguishing between benign and malignant tumors and for assessing the extent of dissemination in such cases. This evidence concerns the gene MUC16 and gastric cancer.