BMPR2 and pulmonary arterial hypertension: Glutaminolysis has been shown to play an important role in RV hypertrophy and RV failure, in PAH and MCT animal models of PH, (56), however, in our model of RV failure, our metabolomic and transcriptomic data indicate that the capacity to oxidize glutamine is not elevated in BMPR2 mutated RV cardiomyocytes.