METTL3 and prostate carcinoma: On a mechanical level, in prostate cancer PC-3 and DU-145 cells, SNHG7 stimulated glycolysis via the SRSF1/c-MYC axis; N6-methyladenosine (m6A) modification by methyltransferase-like 3 (METTL3) boosted SNHG7 stability (40).