MTOR and neoplasm: The function of lncRNAs in regulation produced from macrophages in the modulation of glycolysis in tumor cells has been shown, and host lncRNA MIR4435-2HG in primary myeloid dendritic cells (mDCs) from elite controllers (ECs) responded to TLR3-stimulated increases in oxidative phosphorylation and glycolytic activity by mTOR signaling pathway participants through the enhancement of immunometabolism activity of primary myeloid dendritic cells in EC by using specific epigenetic alterations on constituents of the mTOR signaling pathway (69).