CD27 and neoplasm: Previous studies (81) have shown that high levels of CD20+ B-cell follicles are highly correlated with the prognosis of gastric cancer, and that the level of tumor-infiltrating CD20+ IgD-CD27- B cells is positively correlated with the overall and disease-free survival of patients with gastric cancer, who have a better survival prognosis when exhibiting high levels of CD20+ IgD-CD27- B-cell infiltration.