The results showed that HSP90AA1, XRCC1, PTGS2, IL-6, GSTP1, TGFB1, HIF1A, SOD2, MAPK3, and PCNA might be key targets for emodin in the treatment of HBV-HCC (Figure 5B). The gene discussed is PTGS2; the disease is hepatocellular carcinoma.