Thus, individuals in various populations harboring CCR2-64I (Angela Covino et al., 2016), CCR5Δ32 (Gupta and Padh, 2012), and CCR5 promoter A/G (Jang et al., 2008) mutations are less susceptible to HIV-1 infection and progress much more slowly to AIDS. The gene discussed is CCR2; the disease is HIV-1 infection.