To further confirm whether overexpression of SFTPC inhibiting EMT process was related to upregulation of SOX7 and inactivation of WNT/β-catenin pathway in vivo, the stable SFTPC-overexpression A549 cells tumor xenograft model and its control model were established via subcutaneous injection of A549-SFTPC and A549-Control cells according to our previous study (25). This evidence concerns the gene SOX7 and neoplasm.