INS and gestational diabetes: Studies show different risk factors associated with the requirement for glucose-lowering medications for glycemic control in singleton pregnancies complicated by GDM such as age, prepregnancy BMI, prior history of GDM, glycated hemoglobin value at GDM diagnosis, and family history of Type 2 diabetes mellitus [10–14] as well as higher fasting and 2-h plasma glucose concentrations during OGTT [15, 16] to be strong indicators for insulin therapy (IT).