INS and gestational diabetes: However, in twin pregnancies, our study found that both the 1-h and fasting OGTT levels were relevant in predicting the requirement for insulin treatment [23] and showed cutoff values of 108 mg/dL for fasting and 215 mg/dL for the 1 h OGTT to be relevant for the initiation of IT, while the measurements for the 2 h OGTT seem to be unstable and not very promising in GDM twin pregnancies.