Key variables driving the separation of AD and controls include inflammatory markers (IL-1a, IL-8), growth factors (EGF), lipids (LDL), BMI, and gut microbes, like genus Tyzzerella and Turicibacter, and species Parabacteroides distasonis and Bacteroides eggerthii (see Figure 4(c)). This evidence concerns the gene IL1A and Alzheimer disease.