The most common TE irAEs (occurring in ⩾5% of patients in either treatment arm) were arthralgia, infusion-related reactions, hypothyroidism, rash, maculopapular rash, alanine aminotransferase (ALT) increased, pruritus, and aspartate aminotransferase (AST) increased (Table 3). Here, GPT is linked to hypothyroidism.