Compared to the non-IR group, participants with IR were older and had more comorbidities, such as diabetes, hypertension, coronary heart disease, acute myocardial infarction, chronic heart failure, stroke, and cancer, with higher levels of systolic/diastolic blood pressure, BMI, ALT, AST, Scr, Hb, HbA1c, TG, TC, and HDL-C. The gene discussed is GSTM1; the disease is diabetes mellitus.