Such intra-adipose events would be further supported by hCG/LH inhibition of AP-1 activation as seen in other cell lines [61, 62], agreeing with the presence of hCG/LH receptors in human SC adipose [63] and the negative correlation of serum log LH levels with SC abdominal adipose AP-1 protein expression in our women with PCOS but not in our controls. Here, PLOD1 is linked to polycystic ovary syndrome.