After these adjustments (Table 2), the difference in intact proviral load between TB and no-TB groups remained statistically significant (median 762; IQR, 183-1173 vs 117; IQR, 24-279 intact provirus per million CD4+ T cells, respectively; P=0.0001) by Kruskal-Wallis test as well as by tobit regression (P<0.0001, Figure 2A). This evidence concerns the gene CD4 and tuberculosis.