sod-1 encodes the ortholog of mammalian SOD1, which is a cytoplasmic SOD implicated in the development of amyotrophic lateral sclerosis (ALS) and cancer (Giglio et al. 1994; Papa, Manfredi, and Germain 2014; Wang et al. 2021; Zhang et al. 2007). The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.