While activation of cGAS/STING normally induces cell death due to interferon/TLR/STAT1, CIN-induced STING signaling resulted in enhanced survival and proliferation due to non-canonical NFKB (RelB) (Bakhoum et al., 2018) as well as IL-6/JAK2/STAT3 signaling (Hong et al., 2022). The gene discussed is STING1; the disease is cervical squamous intraepithelial neoplasia.