KIF2C and cervical squamous intraepithelial neoplasia: Despite being a significant endogenous stress that limits transformation potential (Morel et al., 2017), studies using specific KIF2C constructs to modify CIN levels (Moore et al., 2005; Bakhoum et al., 2009) have shown that CIN can paradoxically enhance tumor progression and metastasis by inducing inflammatory signaling (Bakhoum et al., 2018; Hong et al., 2022; Li et al., 2023).