CXCL8 and colorectal carcinoma: The influence of the methodological ability to evaluate biomarkers for CRC screening on the AUC was striking when looking at interleukin (IL)‐8, with an AUC for CRC detection between 0.92 and 0.98 in poor‐ability studies, 0.76 in a medium‐ability study, and only 0.68 in a good‐ability study (Fig. 2).