Additionally, compared to ICH patients without HE, patients with HE were more likely to have larger baseline hematoma volume, higher ratios of irregular hematoma and hematoma with mixed density, lower baseline albumin, higher baseline monocyte count, and blood glucose as well as prolonged prothrombin time and activated partial thromboplastin time (all p < 0.05). Here, F2 is linked to hereditary elliptocytosis.