Investigating instead putative direct RNA silencing, among the targets predicted for DCL2-dependent milRNAs and supported by target prediction, opposite expression, and Spearman anticorrelation significantly higher than the one with the average transcript, we found one 3.A.1.208 ABC transporter (CRV2T00011673_1), a class responsible for multidrug resistance in cancer cells [96]. The gene discussed is ABCG2; the disease is cancer.