PRKCA and myotonic dystrophy type 1: As analyzed by immunoblot of CELF1 and EMT markers, knockdown of PKCα in TGF-β-treated MCF-10A cells essentially abolished both EMT and CELF1 expression (Fig. S5A), consistent with previously described observations in MCF-10A cells (28) and suggesting a relationship somewhat functionally analogous to that previously described in DM1 models (17, 27).