MGMT, which encodes the DNA repair protein O6‐alkylguanine DNA alkyltransferase, is ubiquitously expressed in human tissues and is often upregulated in malignant tissues.[47] MGMT promoter methylation correlates with decreased progression‐free and overall survival in patients with GBM treated with alkylating agents. Here, XRCC6P5 is linked to glioblastoma.