The results showed that HDAC3 enrichment in the SOX9 promoter region was significantly decreased in Linc00942‐overexpressing and MUT‐1 GBM cells and that the interaction of STAT3 with the SOX9 promoter region was significantly increased in Linc00942‐overexpressing and MUT‐2 GBM cells compared with scrambled control cells. This evidence concerns the gene LINC00942 and glioblastoma.