SOX9 regulation by HDAC3 and STAT3 has been reported in several studies, and the inhibition of HDAC3 and activation of STAT3 leads to the elevation of SOX9 expression.[64, 65] Based on the ChIP‐Seq data, the ChIP‒qPCR assay revealed that the enrichment of H3K4ac and p300 at the SOX9 promoter was significantly increased in Linc00942‐overexpressing GBM cells and TMZ‐resistant GBM cells, but not in MUT‐1 and MUT‐2 cells. This evidence concerns the gene EP300 and glioblastoma.